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My Buddy Eric 

My Buddy Eric has dedicated his life to doing everything no matter how obscure and to being the buddy of as many people as possible.
Person 1: hey, my buddy Eric did that!
Person 2: hey, mine too
My Buddy Eric by K.F.K. January 26, 2022

This happened to my buddy Eric 

It refers to a review of the 2019 film Joker on the platform of Letterboxd, indicating that their friend Eric also had a phase and became like the Joker. It received widespread forwards and shares on social media making it an iconic review with regards to letterboxd.
This happened to my buddy eric is such an overused meme, it's annoying.
Someone who constantly refers to their friends as "my buddy (insert name here)", even though you may have met that person 100 times.

This person generally has so many cousins and aquaintances that he can't keep track of who knows who - he is only confident that he knows everyone. Or at least knows someone who knows someone who knows everyone.
Harsh: Dude, what's up for this weekend?
Johnny: My buddy Powers is having a Halloween party on Saturday, should be epic.
Harsh: "My Buddy Powers"? Dude, I've met the kid 100 times, you can just say "Powers".
Johnny: Fuck yo couch. That's what my buddy PJ always says.
Harsh: Jesus christ.
My Buddy by mikepo21 October 31, 2012
My buddy was a large doll that was marketed for boys. It had a large head and plush body and was supose to be "a boy's best friend." Parents who were against violence usually bought this doll as a replacement for G.I. Joe.
My brother got one for christmas one year, that doll is just creepy. Like a dolled up version of chucky.
"A my buddy doll! I wanted a G.I. JOE!"
my buddy by crystal_pepzi September 22, 2006

Oh My Buddha 

An alternative to "Oh my God", commonly used around strong Christains and anyone else who might be offended by using God's name in vain. ((In extreme cases can be used as "Oh Someone Else's Buddha" if you are Christian, too, or "Oh My Buddha whom I do not believe in"))
Oh my Buddha! Did you see that spaceship fly overhead!?
Oh My Buddha by KelseyKarma December 28, 2007
a gun.. or perhaps a knife or other weapon but mainly a gun
"my buddy my buddy wherever I go he goes" 50 Cent and G-Unit
my buddy by dymedoutmami315 December 28, 2003