Top Definition
To back out of doing something because you're too much of a wuss to follow through, or to break down because you can't handle something.
Emma totally muffined out of going to track practice.

Andrew was complaining he was tired, I think he's going to muffin out of going out tonight.

Beth muffined out during the chemistry test, she was crying for an hour.
by kiki1987 March 20, 2013

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