The roll of fat which hangs over the waistline of a girl's pants/skirt which isn't covered by the top she is wearing (like the way a muffin hangs over the paper base).
"That girl shouldn't be wearing that crop top and those low riders..."
by Watch out for Scary Fat Chicks... May 15, 2005
a chain of coffee/muffin stores, whose name is commonly used for describing the period of muffing a chick, when one 'comes up for air'
"it felt like hours i was down there, i had to take a muffin break"
by petey April 01, 2004
Having To Take A Shit.
"Dayum Ma, I Gotta Take A Muffin Break."
by -chelly* May 12, 2007