Dandruff i.e. white flakes of skin on your muff
Urr miss look at her she's got muff-druff
by Nicola1 September 29, 2007
1 more definition
Top Definition
Dandruff from the female pubic region.
Whoa - you need to get down with the Head & Shoulders to treat that muffdruff!
by Duffstar June 29, 2005

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