1. a seriously ugly bitch, not even worth the time of day.
2. an ugly cunt.
3. a bitch who is an ugly person on the inside, not necessarily the outside.
1. Ew, ignore that mufafa, she ain't worth it.
2. Look at that mufafa.
3. Person 1: Karen is so hot but she is such a bitch. Person 2: She's such a mufafa.