A television show with Robin Williams that ran from 1978-1983. An alien named Mork from the planet Ork lives with his girlfriend. Mork has hilarious catchphrases such as Nanu Nanu and Shazbot. The creators changed around the show though and ruined it. Mork even had a son that aged backwards named Mearth. Don't mess with perfection.
Man 1: Did you see the rerun of Mork and Mindy last night?

Man 2: You bet! Nanu Nanu, shazbot!
by Clint1930Eastwood December 31, 2014
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When you take 2 oppositely affecting drugs, usually a stimulant and a depressant, at the same time.
Hey bro, wanna do a Mork and Mindy tonight?
by Bigpeenbean March 5, 2021
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