mef mouf Share definition Flag A physical malformation resulting from the over-consumption of the popular party drug mef, or "mefamphetamine." If you don't lay off the mef, you're gonna get da mef mouf. mef mouf by ericalexander June 29, 2011 0 0 Get merch Get the mef mouf mug. Buy Now — $32.95 See more merch
