"My mans and 'em" is a more recent of urban phraseology, made popular by the prolific rapper/actor DMX (Dark Man X). It means "my friends."
See why my "mans and 'em" call me the Benjamin Banneker of the 20th and 21st
by bobo February 21, 2003
1 more definition
The name guys give for their penis and balls.
Hey baby, you wanna meet my mans and 'em?
by Krazee 8 May 19, 2005