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1.
A male that acts like a little bitch. Could also be a nickname. Mainly used just for fun. Sometimes a dis... or could be a compliment.
i.e. Quit bein such a "mandyke" and drink it!

i.e. Person 1: Hi, what is your name?
Person 2: They call me Mandyke!

i.e. (In perhaps a game of Madden or other similar situations.) "Hey nice play mandyke. Just don't let it happen again.
by Mas October 02, 2003