mad acne; excessive amounts of acne.
Dude, check out that girl. She got macne.
Acne caused by constantly wearing a layer of MAC makeup to cover up minor acne, which then becomes huge and insane and requires even more MAC to cover up, leading to more MACne forever until your face explodes. Common among scene boys and girls.
I thought he was hot, until he came out of the shower and his face was a MACne battlefield.