Top Definition
To have a complete mental and physical breakdown as a result of someone's jackassery or assholery.
When I mentioned I wanted to become a woman, my girlfriend totally lost her shit.

Good grief, if you kids don't stop with this jackassery, I'm going to lose my shit!
by groovygrrl October 13, 2004

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Verb. To become so overwhelmed with excitement or euphoria that a person literally shits themselves, often without realising or caring.
To lose one's shit:

"You should have seen him - he was so happy with the result that he lost his shit!"

"Her crush made eye contact with her and smiled, and she lost her shit."
by Sakura44 June 20, 2016

The Urban Dictionary Mug

Lotsa space for your liquids.

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The Urban Dictionary Mug

Lotsa space for your liquids.

Buy the mug

The Urban Dictionary Mug

Your favorite word on a white mug.

Create a mug

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug

The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

Buy the t-shirt

The Urban Dictionary T-Shirt

Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

Buy the t-shirt