1. Possibly the most extreme, blasphomous term to use when one is surprised and/or outraged in the english language.
2. Used as a term to say something random but incomprehensible for a few seconds to the person the term is directed to.
Situation 1:

Somone busts into a room with an AK-47 and shoots the person right next to you.

Your response: Jesus fucking Mary doggystyle Christ!

Situation 2:

Johnny: Sooooo...
Mike: hmm....
Chris: yeah...
Dalton: JESUS FUCKING MARY DOGGYSYLE CHRIST!
Johnny: wtf happened?
Mike: oh my stars
Chris: lollerpops
by MrDinkleberry November 21, 2005
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A verbal expression of overwhelming fear when a person is startled, surprised, shocked, or scared followed by extreme anger.
While Jimmy is driving on the expressway, he is suddenly cut off by another vehicle traveling ten miles per hour under the speed limit. Jimmy: "Jesus Fucking Christ Hole! You cut me off! get the fuck out of the way!"
by poop master general October 14, 2022
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when ur actually severely injured and.......
Rob: JESUS FUCKING CHRIST MY FUCKING ARM IS FUCKING CUT OPEN LIKE A PUSSY GOD HELP THE FUCKING PAIN FGFHTDGHFHGDHDFSGRSGHFFUUUUUUUUUUUUUUUUCKKKKKKKKKKKKKKKKKKKKKKKK KKKKK *inhales* AHAGAGAHGAGAHYHAHAAAAGAGAGGGAGAAAAAAÀÆAAAAAA *lungs start to collapse* HAGHAGHAGAHHGAGAGEEEAAAAAAAAA WHYYYYYUUUUUU AUGEGHGHGHGHGAAAAAAAAAAAAAAA *right lung is collapsed* LORD PLEASE SEND ME TO HEAVEN BEFORE I DIE I'M SORRY FOR BEING HORNY, WATCHING HENTAI, AND JERKING OFF, AGAHAGAFGFFGAAAAAAAAAA *fucking dies*
by XxXdickblue1XxX November 16, 2021
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