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Iocane Powder 

A highly toxic substance with origins in Australia. Immunity from the deadly properties of iocane can be built up over a period of time if it is introduced in minute portions.

As read/seen in "The Princess Bride": the name was most likely derived from a slightly altered anagram for cocaine, a commonly used drug during the time the book/movie were written (1973, 1987 respectively)
Buttercup: "And to think, all that time it was your cup that was poisoned!"
Man in black/ Westley : "They were both poisoned. I've spent the last few years of my life building up an immunity to iocane powder."
Iocane Powder by Whompy Geeb September 3, 2011
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iocane pussy 

A vagina that does not taste or smell like anything.
Iocane pussy is odorless, tasteless, and is among the more deadly poisons known to man.
iocane pussy by Jacob Mehoff September 18, 2008
Related Words
A boy who knows how to treat girls right. Usually happy but when he's sad you can tell. tall, dark hair and eyes. Very athletic and popular. funny and smart. Good kisser and nice body. BUSHY EYEBROWS
p1:wow look at him
p2:yeah! what a Ioane
p3:yeah you can see it in the eyebrows
ioane by PETTY PATTY13 May 18, 2016
Extrovert but simultaneously an introvert.
Very ambitious and passionate.
Daring and a risk taker.
Embodies both the kindness of Keanu Reeves and confidence of Beyoncé.

Damnnn I wish I was a Ioane!
Woah, such a good balance of character. Must be a Ioane!
ioane by wetdiaperssuck July 21, 2017
Doing the rubix cube while getting sucked off.

Whenever you finish before you "finish" its called a Lam chop.
You're disqualified if you jizz before you solve the cube and that my friends is called a Ning Lam.
If your chick gets bored then thats what we call a beldi...
Friend1: How was the interview man?
Friend2: Didn't get it. Went home and pulled a ioane instead.
Friend1: (LOL) How'd you go?
Friend2: Almost had it! Then she beldi'd out on me...
Friend1: Useless man you are pathetic
ioane by doctor chinaman September 4, 2010

Iocaine powder 

(Fictional). A powerfully deadly & undetectable poison originating from Australia. Both colourless and odourless (in Australia, the correct spelling of those words), iocaine powder will dissolve instantly when poured into a liquid. However, starting with a tiny dose and carefully increasing consumption over time, one can build up a tolerance to iocaine.

The substance was introduced in "The Princess Bride" (1973), a novel by William Goldman, where it featured in a battle of wits between the Sicilian criminal genius, Vizzini, and the mysterious Man in Black. The scene was later depicted in the movie "The Princess Bride" (1987). References to Iocaine powder have subsequently been made in movies "The Haunted Mansion" (2003) and "Jack and the Beanstalk" (2009). In the latter, it's mentioned by the pawnbroker played by actor Wallace Shawn, who starred as Vizzini in "The Princess Bride".

Iocaine is sometimes misspelt as "iocane". The correct spelling is modelled after that of the real drug cocaine (from "coca" (the plant which produces the drug) + the chemical suffix "-ine"). It would appear that the pronunciation of the name of this poison, "I owe Cain", is a subtle reference to Cain, the first murderer (Genesis 4:8) —although it should be noted that Cain killed with some kind of physical violence, not with poison.
Buttercup: “And to think, all that time it was your cup that was poisoned!”
The Man in Black : “They were both poisoned. I've spent the last few years of my life building up an immunity to iocaine powder.”

Iocaine powder 

(Fictional). A powerfully deadly & undetectable poison originating from Australia. Both colourless and odourless (in Australia, the correct spelling of those words), iocaine powder will dissolve instantly when poured into a liquid. However, starting with a tiny dose and carefully increasing consumption over time, one can build up a tolerance to iocaine.

The substance was introduced in "The Princess Bride" (1973), a novel by William Goldman, where it featured in a battle of wits between the Sicilian criminal genius, Vizzini, and the mysterious Man in Black. The scene was later depicted in the movie "The Princess Bride" (1987). References to Iocaine powder have subsequently been made in movies "The Haunted Mansion" (2003) and "Jack and the Beanstalk" (2009). In the latter, it's mentioned by the pawnbroker played by actor Wallace Shawn, who starred as Vizzini in "The Princess Bride".

Iocaine is sometimes misspelt as "iocane". The correct spelling is modelled after that of the real drug cocaine (from "coca" (the plant which produces the drug) + the chemical suffix "-ine"). It would appear that the pronunciation of the name of this poison, "I owe Cain", is a subtle reference to Cain, the first murderer (Genesis 4:8) —though it should be noted that Cain killed with some kind of physical violence, not with poison.
Buttercup: “And to think, all that time it was your cup that was poisoned!”
The Man in Black : “They were both poisoned. I've spent the last few years of my life building up an immunity to iocaine powder.”