From the mispronunciation of julius in Orange Julius. To call someone a hoolius is like calling someone stupid, or making fun of them. Though it sounds mean, it is really a term of endearment.
Person 1: "Man, did you see Seth today? He was like, crawling on the floor and sh*t"
Person 2: "Yeah man, he's such hoolius. But we still love him."
by NinjaWildebeast December 19, 2010

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