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1.
To bear down, grit it out, stay the course

Originally a nautical term probably borrowed from the Dutch "houd vast" (hold tight) referring to the importance of securely gripping a ship's rigging.
Times are tough right now but we got to hold fast and ride it out.
by yoopah10 June 19, 2013
 
2.
To stop or slow down
Aye hold fast for a min
by Phillie Phil September 13, 2005