Top Definition
what someone becomes when he or she goes out on a limb to try something new or risky and ends up having his or her plan fail completely.
Theorizing that the more I studied, the worse I do on tests, I didn't study for my comp sci test and I failed. I was the guinea pig of my own demise.

In Spider-man, when Norman Osborne conducted experiments on himself that lead to his insanity and death, he was the guinea pig of his own demise.

(variations of "guinea pig of one's own demise")
by mbriones January 25, 2012

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