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1.
1. (verb) to make ghetto
2. (verb) The process of making something or someone ghetto that was not previously in this state.
Yo, you need to ghetto-ize that shit befo those niggas bust a cap in yo ass
by scubasteve90 January 22, 2011
 
2.
The opposite of de-ghettoize, refers to the vast influx of poor bad minorities into inner-city neighborhoods that were left to rot by rich white people; later the rich white people realized they missed their cities and began a process of de-ghettoization, which consisted mostly of "running the Richard C. Lee Memorial Highway through it."
That mall really helped ghettoize downtown.
by AhmedKazikian January 18, 2005