Top Definition
The act of maintaining a ghetto disposition that is on and off regardless if you get out of the ghetto. It has already permeated your head. A term used in New York City to describe people to have a continually ghetto character mad randomly wherever they may move or go.

John: Hi Marie
Marie: O Hi John


John: Hi Marie
Marie: Fuck You, Just Kidding

John & Friends: Damn the Hood done permeated her brain. She Got Ghetto Osmosis.

by Winmobmak384 March 31, 2009
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