Top Definition
A term I often use describing something that has been heavily tailored to meet a certain specification.
Benjamin Button was genetically-modified to win Movie of the Year.

Political speeches are genetically-modified, heavily-edited bullshit.

Valve brilliantly genetically-modified their marketing strategies and games to generate lots of sales while using the least amount of (game-developing) effort by well-placing updates, patches, SDKs, price drops through Steam and game sequels.
by Miyamiya July 31, 2009
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