Top Definition
What happens to your thumb after playing 2 or more consecutive hours of video games, especially games where you have to continuously tap buttons to get up and/or use the analog sticks.A blistered, red sensitive thumb. See nintendo thumb and playstation thumb.
If you play a Def Jam game, game thumb is a given. Bet on it.
by Nastina September 07, 2005
2 Words related to game thumb
Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.