the last drink before someone passes out from too much alcohol.
the drinker usually has asked for "one more" drink before the fourth drink instinct takes effect, letting the drinkers friends know that they are going to pass out.
The fourth drink instinct let us all know that kelcie was about to pass out after one to many vodka shots
by Catyy May 29, 2007

5 Words Related to fourth drink instinct

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