A derivative of the words 'Fo Sho' which in turn is a derivative of the words 'For Sure' It was originated by the Doggfather, big Snoop Dizzle aka Snoop Dogg aka Snoop Doggy Dogg, also creator of the term ' DEEZ NUTZ'
"Man, that girl is fine,"
"Fo Shizzle my Nizzle"
by Ron H, April 09, 2007
A response to an inquiry or statement so obvious or certain that saying, "For Sure," just wouldn't do it justice.

Due to its popular over-useage in the early 21st century, it is now reserved for use on special occasions when that extra emphasis is needed.
"Do you want to live?"
"Fo Shizzle!"
by geminigod July 26, 2012
stands for fo shizzle my nizzle, which stand for, For sure my nigga, which also stands for "I whole heartedly agree my my fellow bretheren of African descent".
Tyrone: yo, You wanna hang?
Dante: Fo shizzle
by IIvoltairII July 23, 2012
My nizzle.
Snoop Dog: Fo shizzle, my nizzle.
Me:For sure, man.
Snoop Dog:Naw, you gotta say it like me.
Me:For sure, I got it.
Snoop Dog:Fo shizzle you don't.
by UnmeiShira May 05, 2011
another word meanin 'for sure' or 'for real'
''u comin out?'' ''fo' shizzle''
by 02wcw July 10, 2009
A saying no one should ever say ever.
Yo dawg! I heard you like shizzle so I got you fo shizzles so yo fo shizzles have shizzles fo shizzle.
by wankster-gangster May 10, 2009
for sure
fo'shizzle ma nizzle
by archi123456 July 10, 2008

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