Top definition
1. When someone has five sexually transmitted diseases at the same time.
(i.e. aids, ghonorea, crabs, syphillis, herpes)
2. When a person who is playing Blackjack is dealt five cards but does not bust.
1. Dude you had better avoid that girl, she's got the five card charlie.
2. I had a five card charlie going but the dealer still got 21.
by T.C. April 14, 2005
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