Originated from Metal Gear Solid 2 Sons Of Liberty. What is different is that they changed the first two letters in order to confuse the player. Sometimes used on messageboards to show defeat or total pwnage.
"That sign said Mission Failed so I turned the power off."

"Dude, it was Fission Mailed, they just tried to confuse you, now you gotta start all over again cause you didn't save. Pwned!
by SCANK April 18, 2005
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A word that is said in occurance when absolute and complete pwnage has been indignantly brought upon by a poor soul.
Allan FISSION MAILED! it when Travis threw a tennis ball at Allan's left nut.
by PLLL0WTALK January 6, 2006
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Derives from the game "Metal Gear Solid 2"

it means "Mission Failed". which is used as a derogative term to slander someone/ someones argument that they've put forward in a debate, it is both patronizing and shows that you're putting an end to the argument.

Considered to be part of l33t sp33k. Gaming slang. Often used as the end of a sarcastic comment.
Oh yeah!! i forgot Lilly Allen does write good lyrics!! ......Fission Mailed.
by Intrinsic_IZ_Clutch July 20, 2009
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A term loosely meaning that you have been embarrassed to the highest degree, similar to pwned and You Got Served

Origin: Metal Gear Solid 2 near the end of the game, there's a screen that says that very phrase that's supposed to mimic the "Mission Failed" message you get when you normally die in said game.
Dude, your girlfriend sucked my cock last night! FISSION MAILED!
by DANfan February 21, 2005
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