used when describing, grimey or sketchy events or areas. refrencing the reality show "FIrst 48" where detectives take you through the first 48 hours of a homicide investigation. Most homicides on the show are in ghettos or projects in large inner cities.
yo! did you see that alley way? thats some first 48 shit right there!
by e.m.s March 28, 2008
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a time in which a guy takes interest and you, and after this time is up you are ghosted
Example: he hasn't texted me back in 3 days, yes because he hit you with the first 48
by Karinbean6969 February 12, 2017
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Most murders are solved in 48 hours, if they are not solved in that time frame they usually don't get solved.
Cop 1: first 48 hours has passed lets go do some hate crimes
Cop 2: Catch the game?
by scrag_10 April 11, 2008
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