The evil fortune that ditcates, when you're playing a video game, everything that can go wrong for you will, while everything that can go right for your opponent will. If you have a 2% chance of missing, you will miss; if your opponent has a 2% chance of hitting, he will hit. You will never critically hit while your enemy crits every other uncannily-accurate strike, and they'll shrug off your most powerful spells and status ailments while crippling you with a minor expenditure of mana.
"Go away enemy luck! I actually want to land a hit before I die!"