2 more definitions
I don't drink, smoke, do drugs, have sex, eat meat or swear. If you don't like that, then eff off, ya big weenie!
by Anonymous October 10, 2003
Go the hell away. Same meaning as WHATEVER and SCREW YOU. Said mostly jokingly or when someone is annoyed.
Karm: Eff off, you annoying POS.
by Miss AnGie January 19, 2003