Out of order; unusual behaviour; operational but not quite to full capacity.
A person who is out-of-sync with their regular routine.
Machine or equipment that is not working properly or is uncalibrated.
Person 1: "Whats the matter? Is something bothering you?"
Person 2: "No, but something has me dysregulated."
"I wouldn't trust the reading on that scale, it's been dysregulated since Fat Mike came to visit."