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1.
phoney beer brand ala the simpsons
by mertyl June 06, 2003
 
2.
A brand of beer drank by Homer Simpson and his friends in popular Television show "The Simpsons". It is the only drink that Moe Syzlack stocks at his tavern, Moe's Tavern.
"Hey Moe, Gimme a Duff Beer, please."- Homer Simpson
by Tuddy September 02, 2007