From the term "downer"
someone who brings people down and it a sort of mood-killer.
Josh is happy he got 93% on his test and Mike walks over and shows him his 95%. Mike is a downie.
by Yosh man January 17, 2010
1)someone with Down Syndrome
2)A Tard
"syndrome of a down are fuckin downie rejects"
by wet water July 11, 2006
1. Someone with Down Syndrome

2. A dumbass
"Damn, The guys in System Of A Down are fuckin Downies!"
by AbominusNeferia July 27, 2005

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