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1.
A false disease made up by a group of boys to have an inside joke. Made up to make girls wonder what the heck kind of disease that they have not knowing that the whole time they are researching Crubes it in fact does not exsist.
Stupid boy to other stupid boy in front of girl: Hey dude did you know she has crubes.

Stupid boy back to other stupid boy in front of girl: Sick........She should see a doctor.

Girl: What....what are they even talking about....(immediately goes home and googling it.)
by Boston McDonald June 03, 2008
 
2.
A new member of the crew/fam.
crew+noob=crube
by calinestonyford September 03, 2010