Top Definition
Creff is a Cincinnati area word that can be used for just about anything; a very flexible word, cref can mean a friend, an event that just happened, or simply an interjection. Cref is whatever the mind that says it dreams it to be.
"Yo, what up, creff!"

"Can I creff a dollar from you?"

"Most creffinitely, homie."

"Creff that shit!"
by Same, creffin' ain't easy. March 23, 2006
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