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1.
The female equivalent of broseph; a female friend.
Don't trip brosephina, the motocross race is still on for tonight.
by A Salamander. February 08, 2008
 
2.
Brosephina is a nickname for your gay bro.
Your gay bro: Hehe, hey bro, i'm going to go buy the new Jonas Brothers album!
You: Whatever Brosephina.
by Bloodbath 87 March 06, 2009
 
3.
1.) A female bro.
2.) Angelina Avalos
Bros and brosephinas, it's time to party!
by Baron Kalanium April 01, 2012