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1.
A mistake or screw-up. "Bozz" or "Bozzed" for short

Origninally a a derivative of the nickname "Bosley" for a young man named Max Pepper who consistently messed things up.
"Man, I can't believe you rented the wrong movie! What a total bozzle!"

"Mia totally bozzled that pep-talk"

After Jess knocked over the wedding cake, everyone at the reception yelled "BOZZLE!"
by JCon May 27, 2004