when you accept the fact that you've lost a possession of your's and you'll never get it back. bill being a reference to the amount of money that the possession is worth. game being a reference to life.
edwin: "i got hella drunk the other night at the bar, and i let this chick take a look at my new iphone. i was so fucked up, that forgot she still had it when i went to go piss. when i came back out, and she was gone. i never got her name."
rick: "man you gotta bill it to the game"