Party district located about 3 miles NE of downtown Tampa. It is a little bit ghetto and can sometimes have some low lives, but there is a lot to do there. Lots of decent-high end clubs (Ampitheater, Fuel, Prana, etc), nice restaurants (Carmines, Columbia), and some fun little shops (sunglass hut, claires, starbucks). Also the best arcade ever (Gameworks) and a movie theater that has a full bar (Muvico Ybor). It DOES get old if you go three times a week but if you go sparingly, is really a great place.
Man I went to Ybor last night, stayed by the bar in Fuel and had a cute latina dance on me!