Top Definition
You only live once, so keep up.

YOLO, from the Drake song, "The Motto," combines with a phrase that rebukes those who haven't kept up with trendy new acronyms.
Person One: SMH, TBH.

Person Two: Huh?
Person One: Shaking my head, to be honest. D'uh. YOLOSKU.
by themottoyolo December 31, 2012
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