An insult*, usually used as a comeback when someone insults your credibility, swag, and sexual orientation. This means many things:

1. By asking him, "Who's yo mans?" you are implying that he is gay and has a pimp.

2. You are calling him a bitch.

3. You are saying that he can't do shit without asking his pimp, and that he's the bottom bitch in his homosexual relationship
.
Using the word "nigga'' at the end will undoubtedly increase the ghetto-ness of the phrase but also imply you are not fucking around. A simple example of this is provided below.

*Can also be used jokingly around good friends.
Tyrone: Ay Dwayne, I heard your Yeezys ain't real.

Dwayne: The fuck did you say? Who's Yo Mans? Huh? Who's Yo Mans, nigga?
by Specks September 19, 2012
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