Top Definition
Similar to Wheel of Fortune, but rather than having a chance to win, you will lose or get something shitty all of the time. Also another good phrase for Roulette.
Sam decided to spin the Wheel of Misfortune, but lost every time.

Jim went to the casino to play the good ol' Wheel of Misfortune and lost his house, car, and kidney because of his debt.
by 1-800-PAIN March 18, 2015

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