The condition that a guy contracts from contact with the vagina of a chick he is totally into. Symptoms include telling friends things they totally don't want to know about your sex life, holding hands in public, going shoe shopping, and not shutting the fuck up about your girlfriend for five minutes.
From Romeo & Juliet, Act 1:

ROMEO

Why, such is love's transgression.
Griefs of mine own lie heavy in my breast,
Which thou wilt propagate, to have it prest
With more of thine: this love that thou hast shown
Doth add more grief to too much of mine own.
Love is a smoke raised with the fume of sighs;
Being purged, a fire sparkling in lovers' eyes;
Being vex'd a sea nourish'd with lovers' tears:
What is it else? a madness most discreet,
A choking gall and a preserving sweet.
Farewell, my coz.

BENVOLIO

sup dude u have vagina poisoning.
by 00200 April 9, 2010
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When a male ditches his friends and family over a vagina because he has been poisoned by said vagina. Symptoms include sudden disappearances, ignored phone calls and texts, utter denial of vagina's ugliness and wrongdoings, and psycho babble about how great the new vagina is. Although this is not contagious, it can be harmful to all those who were close to the male suffering from vagina poisoning. Almost all cases of vagina poisoning have been spawned by a succubus.
Q: Why hasn't John returned my texts and why is he still seeing Laura after she cheated on him?

A: He has vagina poisoning.
by Ginger I. Tis August 16, 2010
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A person who is incapable of getting any bitches
Person 1: Kevin is just vagina poison

Person 2: Tell me about it he gets zero bitches
by Vaginapoison September 8, 2022
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