Top Definition
A game of spite where one person squeezes a seemingly impossible blob of toothpaste out of the nearly-used-up toothpaste tube, thus making it even harder for the next person to squeeze out toothpaste.
L: "Wow - I thought we finished that tube yesterday"
M: "I just squeezed a blob, now you're up. It's Toothpaste Jenga, baby."
by mjbiz3000 September 17, 2009

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