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1.
1. A football term used to describe when a team fails to get a first down and makes three useless plays and then punts to the other team.

2. A lightweight who can only drink three beers and is then "out" and not needing any more alcohol because they are already drunk.
1. Wow the Steelers are sucking, they need to do something besides these three and outs!

2. Why did you get a whole case when those two are just gonna go three and out?
by J-storm October 28, 2010