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1) The situation of an absence of horse-bodied men from the old English city of Oxford.

2) An exclamation caused by a ridiculous long-term belief being realised to be impossible.
1) "I haven't seen any of those horse-bodied men about this city of gleaming spires lately..."
"Well of course, there are no centaurs in Oxford!"

2) "What?! The Moon isn't made of cheese?"
"Isn't that obvious? There are no centaurs in Oxford!"
by Thursday0901 March 13, 2012