Top Definition

1) Absolutely any woman that your girl works with that has slighted her in anyway (this can be someone who was a best friend two days ago.)

2) The woman who for one reason or another will not give you any nookie.
Her: Do you know what Amy did today?

You: Who's Amy?

Her: That Bitch From Work (TBFW)

You: You saw that tight ass skirt she was wearing today?

Your Friend: Who?

You: That Bitch From Work (TBFW)
by silicone happy March 11, 2011

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