The hangover that one has after having a big night involving the consumption of numerous tequila based beverages is referred to as being chased by the tequila alligator. Tequila is well renowned for giving its drinkers fierce hangovers and so the discomfort associated with a hangover from drinking tequila is comparable to getting mauled by an alligator.
Pedro: "Hey man, how are you feeling after last night?"
Sanchez: "Pretty rough, I can feel the tequila alligator chasing me"
by psco4963 April 17, 2011

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