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1.
Acts as a curse word. Means the same as every cuss word ever!
Oh, tamble!, You tamble!, Go to tamble!, Tamble you!, Tamble hole!, You mother tamble!, God tamble!
by Tamble555 May 25, 2012
 
2.
in a terrible, shattered state of being

The step-up of shambles
The Southern portion of the United States after the American Civil War was in tambles.
by APUSHNERD January 07, 2010