TS^2 

Toxic shock syndrome. When a lazy female is on her period and she leaves a tampon in her vagina for 3 or more days without removal; ignoring all the warning labels. Thus causing bacterial toxins to build up until she develops the rare and serious illness making her turn into an even bigger bitch.

Ed: "Sally's being a total bitch, what's her deal?"
Tom: "She's ts squarin (ts^2)!"
Ed: "Totally"

TS^2 by Mikito-san December 4, 2009