When you put your iPod on shuffle at party or social gathering and you project yourself forward thinking "What's it going to play next?" Jarvis Cocker is often credited as coining this term.
Guy 1: "Dude this is awesome. Those songs transitioned into each other perfectly. I wonder what it's gonna play next"
Guy 2: "Oh no, what is it gonna play next?! Will it be as good?!?"
Guy 1: "Dude you're getting Shuffle Anxiety"
by The Rhys March 30, 2009
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