She-dog is an old southern expression used to infer a particular woman is like a female dog - and will "do it" with practically any male that comes along. (i.e., a slut).
Usage: I don't know how John Mike can trust any of those young-uns are his, that wife of his ain't nuthin' but an old she-dog.
by BearLite July 03, 2013
by LavaGirl GAH! October 07, 2006
by aaronak May 02, 2006