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1.
Shamoozle is the trademark word of comedian 'Ell Da Peach' The word is used as a greeting and also to communicate boredom or indifference
'Hey, shamoozle bruv'

'Shamoozle, whats goin down?'

'Awwww shamoozle'
by The Big Dawg July 23, 2006
 
2.
An extremely fat woman who smells horribly of low tide
Shamoozle really stunk up Blain's office today
by bob yuiloiujkjhu May 20, 2008